IGF-1 DES

IGF‑1 DES (1‑3) – Precise Peptide for Advanced Cellular Research

Designed for laboratories that demand exacting molecular definition, IGF‑1 DES (1‑3) delivers a rigorously characterized peptide suitable for studies of growth factor signaling, metabolic pathways, and cell differentiation. Each batch is accompanied by full analytical documentation, ensuring that researchers can verify sequence integrity, purity, and composition before initiating experiments.

What it is

IGF‑1 DES (1‑3) is a truncated analogue of the mature insulin‑like growth factor‑1 (IGF‑1) molecule, lacking the N‑terminal three amino acids. This structural modification reduces affinity for several IGF‑binding proteins, thereby altering the peptide’s availability in vitro and providing a distinct tool for dissecting IGF‑1 receptor‑mediated mechanisms. The sequence is precisely defined, and the product is supplied as a lyophilized powder with a confirmed molecular weight of 7,641 Da.

Key Highlights

• Defined truncation: Missing residues 1‑3 compared with full‑length IGF‑1, creating a unique binding profile.
• Reduced IGF‑binding protein interaction: Lower sequestration by IGFBPs enhances free peptide concentration in cell‑based assays.
• High purity & analytical certainty: Certified ≥ 98 % purity confirmed by HPLC, mass spectrometry, and amino‑acid analysis.
• Consistent batch‑to‑batch identity: Full sequence verification and peptide mapping provided with every shipment.
• Versatile research applications: Ideal for probing IGF‑1 receptor signaling, metabolic regulation, and differentiation studies across diverse model systems.

By delivering a peptide with a clearly documented molecular identity and a predictable interaction profile, IGF‑1 DES (1‑3) empowers researchers to generate reproducible data and draw precise conclusions about IGF‑1‑related pathways. Choose this specialized analogue to expand the scope of your investigations while maintaining the highest standards of analytical confidence.